IMidazo[1,2-a]pyridine-5-acetic acid

IMidazo[1,2-a]pyridine-5-acetic acid - Names and Identifiers

Name	IMidazo[1,2-a]pyridine-5-acetic acid
Synonyms	IMidazo[1,2-a]pyridine-5-acetic acid Imidazo[1,2-a]pyridin-5-ylacetic acid 2-(IMidazo[1,2-a]pyridin-5-yl)acetic acid
CAS	175143-91-6

IMidazo[1,2-a]pyridine-5-acetic acid - Physico-chemical Properties

Molecular Formula	C9H8N2O2
Molar Mass	176.17
Boling Point
Storage Condition	2-8°C

IMidazo[1,2-a]pyridine-5-acetic acid - Introduction

IMidazo[1,2-a]pyridine-5-acetic acid is an organic compound whose chemical structure contains two ring systems, imidazole and pyridine. Its molecular formula is C11H8N2O2 and its molecular weight is 204.19g/mol.

IMidazo[1,2-a]pyridine-5-acetic acid is a colorless to pale yellow crystalline solid. It has moderate solubility and is soluble in common polar solvents such as ethanol, dimethyl sulfoxide and chloroform. Its melting point is about 165 to 168 degrees Celsius.

IMidazo[1,2-a]pyridine-5-acetic acid has a wide range of applications in the field of medicine. It can be used as a drug intermediate for the synthesis of various bioactive molecules, such as anti-inflammatory drugs, anti-cancer drugs and so on. In addition, it can also be used as a catalyst and ligand in organic synthesis, participating in olefin fluorination reaction, Suzuki reaction, etc.

There are two main methods for preparing IMidazo[1,2-a]pyridine-5-acetic acid. One is prepared by the condensation reaction of imidazole and pyridine, and acidic conditions such as sulfuric acid are commonly used in the reaction. The other is prepared by the reduction of imidazo [1,2-a] pyridin -5-one by reaction with acetaldehyde.

When using and handling IMidazo[1,2-a]pyridine-5-acetic acid, you need to pay attention to the following safety information: It is an organic compound with certain toxicity, may cause irritation and damage to the human body. Personal protective equipment, including glasses, gloves and laboratory suits, is required during operation. Avoid inhaling the dust or vapor of the solution. If you accidentally come into contact with skin or eyes, rinse immediately with plenty of water and seek medical attention. At the same time, IMidazo[1,2-a]pyridine-5-acetic acid should be stored in a dry, cool, well-ventilated place, away from direct sunlight.

Last Update：2024-04-09 21:11:58